Analysis of GW0742 docked into PPARβδ (A

gw0742  GW0742 GW0742 is a PPARδβ agonist GW0742 Clinical data ATC code  GW0742 is a synthetic, potent and selective PPAR-βδ agonist PPARs are ligand-dependent transcription factors which are involved in many physiological

GW0742, also known as GW610742 and GW0742X is a PPARδβ agonist GW0742 Induces Early Neuronal Maturation of Cortical Post-Mitotic Neurons  Conclusion GW0742 reduces the cellular and molecular changes occurring in SCI by targeting different downstream pathways modulating PPAR-δ receptors Three

Avis client GW0742 is a potent PPARβ and PPARδ agonist, with an IC50 of 1 nM for human PPARδ, and EC50s of 1 nM, μM and 2 μM for human PPARδ, PPARα, and GW0742 controls Type 1 Diabetes in rats Studies have shown that GW0742 has off target, non- PPARβδ effects in the cell although there are